How to Prepare for Allergy Skin Testing

Stop Taking the following medications prior to skin testing:

Anti-H1 histamines Rx, over-the-counter pills and nasal sprays for about 5 days

  • Levocetirizine (Xyzal)
  • Desloratadine (Clarinex)
  • Diphenhydramine (Benadryl & others)
  • Hydroxyzine (Atarax)
  • Chlorpheniramine (Chlor-Trimeton)
  • Cetirizine (Zyrtec & others)
  • Fexofenadine (Allegra)
  • Azelastine (Astelin, Astepro, Optivar, Dymista)
  • Cyproheptadine (Periactine)
  • Clemastine
  • Brompheniramin (Bromphen)
  • Mequitazone
  • Mizolastine
  • Meclizine (Antivert)
  • Promethazine (Phenergan)
  • Terfenadine (Seldane)
  • Astemizole (Hismanal) stop 30 to 60 days prior to skin testing
  • Anti-H2 histamines Rx and over the counter, certain heartburn medications

Anti H2 histamines, Rx and over-the-counter; certain heartburn medications

  • Ketotifen 5-7 days
  • Cimetidine (Tagamet) 1-3 days
  • Ranitidine (Zantac) 1-3 days
  • Phenotiazines (Thorazine) 1-5 days

Tricyclic antidepressants
Please contact your prescribing physician before discontinuing these medications, if taken daily
Such as nortriptyline (Pamelor) and desipramine (Norpramin), amitriptyline, clomipramine, doxepin (Sinequan), imipramine can interfere with skin testing as well serotonin reuptake inhibitors. Antipsychotics: chlorpromazine (Thorazine), haloperidol (Haldol)

Asthma medication
Omalizumab (Xolair)

Herbal supplements
including: green tea, licorice, saw palmetto, st. John's word, feverfew

If you are unable to restrict these medications as requested, or have any other questions, please let us know.

You can take nasal steroids and inhalers, such as:
Nasacort AQ
Rhinocort AQ
All inhalers


Allergy Season Tips

It's impossible to completely escape pollen and molds; here are some other ways to lessen exposure:

  • Keep windows closed and use air-conditioning, if possible. Automobile air conditioners help, too.
  • Remember to change your home and auto air filters and replace them with high efficiency filters.
  • Outdoor air usually is most heavily saturated with pollen between 5 a.m. and 10 a.m., so early morning is a good time to limit outdoor activities. Mold spores, however, are released due to wind, or other activities that stir them up.
  • Wear a NIOSH-rated 95 filter mask when mowing the lawn, raking leaves or gardening and take appropriate medication beforehand.
  • Use your allergy medications as prescribed daily to prevent allergy exacerbation.
  • Do not forget you allergy shot even is you are feeling OK. Remember you need to complete course of treatment in order to benefit from it.


Request for medical records (PDF file)

Nasal Symptom Evaluation (PDF file)

Patch Test Instructions (PDF file)


Asthma Control Test

What is Sublingual Immunotheraphy (SLIT)?

For Kids With Asthma & Obesity: Which Came First?

Egg Allergic Children Now Have No Barriers to Flu Shot

10 Warning Signs of Primary Immunodeficiency

Allergic Rhinitis and Hospital Readmission


The American Academy of Allergy, Asthma and Immunology

The American College of Allergy, Asthma and Immunology

Food Allergy Research & Education

Kids with Food Allergies

The Allergy & Asthma Network

The Asthma & Allergy Foundation of America

The Immune Deficiency Foundation